Tubulin-colchicine-vinblastine: stathmin-like domain complex
Primary Citation
Structural basis for the regulation of tubulin by vinblastine. (PubMed)
Gigant, B., Wang, C., Ravelli, R.B., Roussi, F., Steinmetz, M.O., Curmi, P.A., Sobel, A., Knossow, M. ─ Nature, 2005. ─ DOI: 10.1038/nature03566
Molecular Description
Classification: Tubulin, Microtubules, Cytoskeleton
Organisms: Rattus norvegicus, Bos taurus
Molecule: Stathmin-4
Polymer: 3 Type: protein Length: 189
Chains: E Related GO annotations
Organism: Rattus norvegicus
UniProtKB: P63043
Molecule: Tubulin beta-2B chain
Polymer: 1 Type: protein Length: 445
Chains: B, D Related GO annotations
Organism: Bos taurus
UniProtKB: Q6B856
Ligand Chemical Component
Image Identifier Name Formula
GDP GUANOSINE DIPHOSPHATE C10H15N5O11P2
GTP GTP C10H16N5O14P3
CN2 CN2 C22H25NO6S
MG magnesium ion Mg+2
VLB vinblastine C46H58N4O9