Tubulin-colchicine-soblidotin: Stathmin-like domain complex
Primary Citation
Structural insight into the inhibition of tubulin by vinca domain peptide ligands (PubMed)
Cormier, A., Marchand, M., Ravelli, R.B., Knossow, M., Gigant, B. ─ Embo Rep., 2008. ─ DOI: 10.1038/embor.2008.171
Molecular Description
Classification: Tubulin, Microtubules, Cytoskeleton, Structural protein, MAP
Organisms: Bos taurus, Rattus norvegicus
Molecule: Tubulin alpha-1C chain
Polymer: 1 Type: protein Length: 449
Chains: A, C Related GO annotations
Organism: Bos taurus
UniProtKB: Q3ZCJ7
Molecule: Tubulin beta-2B chain
Polymer: 2 Type: protein Length: 445
Chains: B, D Related GO annotations
Organism: Bos taurus
UniProtKB: Q6B856
Molecule: Stathmin-4
Polymer: 3 Type: protein Length: 189
Chains: E Related GO annotations
Organism: Rattus norvegicus
UniProtKB: P63043
Ligand Chemical Component
Image Identifier Name Formula
GDP GUANOSINE DIPHOSPHATE C10H15N5O11P2
GTP GTP C10H16N5O14P3
MG magnesium ion Mg+2
LOC Colchicine C22H25NO6
TZT Soblidotin C39H67N5O6